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 YSS Slides 2018 March

PDF renditions of the powerpoint presentations can be viewed and downloaded from this page by clicking the specific point on the program. The program itself can be viewed and downloaded by clicking here.

Program details of the EBF 4th YSS

The BioA Brain Embracing New Ideas

Friday 16 March 2018
09:00 10:20 Session 1:  Alternative sampling having an impact
09:00 09:05 Laura Mercolini (University of Bologna)
Introduction to the session
09:05 09:20 Sofie Velghe (University of Ghent)
Volumetric absorptive microsampling as an alternative tool for therapeutic drug monitoring of first-generation anti-epileptic drugs.
09:20 09:35 Michele Protti (University of Bologna)
Enhanced stability and detection window of large and small molecules prohibited in sports by urine microsampling
09:35 09:50 Bas Sleumer (PRA Health Sciences) not released for publication
Orexin 2: M16 and M12 – the bold and the beautiful! – Determination of a drug and metabolite M16 and M12 in rat plasma using capillary micro sampling and LC-MS/MS
09:50 10:05 Lisa Delahaye (University of Ghent) not released for publication
Volumetric absorptive microsampling for the combined determination of paracetamol and its cysteine adduct
10:05 10:20 Neus Fabregat Cabello (University of Liège)
Dealing with small sample volumes and analyte levels: the case of vitamin D metabolites in aqueous humor
10:20 10:40 Poster pitch (2-minute poster pitch for posters entering the 2018 YSS Best Poster competition – participation is voluntary for each poster submission)
10:40 11:30 Coffee break and Poster Viewing
11:30 12:30 Session 2:  Overcoming Bioanalytical issues
11:30 11:45 Natalie Corden (LGC) not released for publication
The Development of a 7 Analyte Method for Measuring Heroin Metabolites in Human Urine by LC-MS/MS
11:45 12:00 Snezhana Traykova (Comac Medical Ltd)
Overcoming extraction challenges of a bisphosphonate drug from human plasma utilizing an LLE with phase separation approach
12:00 12:15 Toon Babylon (UCB Biopharma) not released for publication
Bridging a classic serum PK assay to Cerebrospinal Fluid: challenges in using surrogate matrices and semi-automation during assay development and validation
12:15 12:30 Barbara Marsiglia (Envigo) not released for publication
Development of a LC-MS/MS bioanalytical method for the quantitation of fragrances in plasma: challenges and troubleshooting in view of validation
12:30 13:30 Lunch break
13:30 14:30 Session 3: MMM – Matrices, Molecules and Methods/part 1
13:30 13:45 Jörg Faber (A&M Labor GmbH)
Best practices for the bioanalysis of endogenous substances
13:45 14:00 Nanda Gruben (PRA Health Sciences) not released for publication
Validation of an ultrasensitive Single Molecule Counting Immunoassay for determination of pharmacokinetics in a regulated environment
14:00 14:15 Estelle Cochet (Novimmune SA) not released for publication
Validation of Biomarker Assays in Disease Populations: Case Study of an Inflammatory Cytokine Immunoassay in Rheumatoid Arthritis (RA)
14:15 14:30 Nikunj Tanna (Waters Corporation) not released for publication
Applying small molecule workflows to large molecule assays – Quantification of IGF-I from biological matrices using LC-MS.
14:30 15:00 Tea break and announcement 2018 YSS Best Poster Prize
15:00 16:00 Session 4: MMM – Matrices, Molecules and Methods/part 2
15:00 15:15 Serge Desmoulins (Agilent Technologies) not released for publication
Drug-to-Antibody Ratio Determination for Antibody-Drug Conjugates in Serum Enbaled by a Sample Preparation Platform that Automates Affinity Purification and Deglycosylation
15:15 15:30 Dan Baker (University of Hertfordshire) not released for publication
Solid Phase MicroExtraction (SPME): towards in vivo sampling of tissues and organs
15:30 15:45 Maria Jadhav (Novartis AG)  not released for publication
Balancing neutralizing antibodies assay sensitivity and drug tolerance in the cell-based systems
15:45 16:00 Sandy Rigot (UCB Biopharma)
Hybrid immunocapture-LC-MS/MS as a powerful and challenging tool to overcome selectivity issues
16:00 16:10 Closing Remarks and Adjourn